Homo sapiens Gene: KCNT1
Summary
InnateDB Gene IDBG-92102.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNT1
Gene Name potassium channel, subfamily T, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000107147
Encoded Proteins
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:135702185-135793150
Strand Forward strand
Band q34.3
Transcripts
ENST00000371757 ENSP00000360822
ENST00000263604 ENSP00000263604
ENST00000487664 ENSP00000417851
ENST00000460750 ENSP00000418777
ENST00000473941 ENSP00000420764
ENST00000486577 ENSP00000417578
ENST00000491806 ENSP00000419086
ENST00000488444 ENSP00000419007
ENST00000490355 ENSP00000418003
ENST00000490363
ENST00000475008
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0015269 calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.104950
RefSeq NM_001272003 NM_020822 XM_006717193 XM_006717194
HUGO
OMIM
CCDS CCDS35175 CCDS65188
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas