Mus musculus Gene: Kcnt1
Summary
InnateDB Gene IDBG-147335.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcnt1
Gene Name potassium channel, subfamily T, member 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000058740
Encoded Proteins
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
potassium channel, subfamily T, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107147:
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:25863795-25918273
Strand Forward strand
Band A3
Transcripts
ENSMUST00000037580 ENSMUSP00000039058
ENSMUST00000114176 ENSMUSP00000109813
ENSMUST00000114172 ENSMUSP00000109809
ENSMUST00000114170 ENSMUSP00000109807
ENSMUST00000150788
ENSMUST00000131529
ENSMUST00000138568
ENSMUST00000128502
ENSMUST00000153001
ENSMUST00000145544
ENSMUST00000171268 ENSMUSP00000132212
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0015269 calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL A2AHB7
UniProt Splice Variant
Entrez Gene 227632
UniGene Mm.401525
RefSeq XM_006497887 XM_006497892 NM_175462 NM_001145403 XM_006497885 XM_006497881 XM_006497880
OMIM
CCDS CCDS15794 CCDS50537
HPRD
IMGT
MGI ID MGI:1924627
MGI Symbol Kcnt1
EMBL AL731682
GenPept
RNA Seq Atlas 227632