Homo sapiens Gene: TRIM62
Summary
InnateDB Gene IDBG-95888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM62
Gene Name tripartite motif containing 62
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116525
Encoded Proteins
tripartite motif containing 62
tripartite motif containing 62
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
TRIM62 is required for TRIF-mediated NFkB, AP-1 and interferon production after LPS challenge in macrophages.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:33145402-33182059
Strand Reverse strand
Band p35.1
Transcripts
ENST00000291416 ENSP00000291416
ENST00000485148
ENST00000486583
ENST00000543586 ENSP00000441173
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
GO:0032897 negative regulation of viral transcription
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087 innate immune response (InnateDB)
GO:0046596 regulation of viral entry into host cell
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:1902186 regulation of viral release from host cell
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9BVG3
TrEMBL
UniProt Splice Variant
Entrez Gene 55223
UniGene Hs.656006
RefSeq NM_018207
HUGO HGNC:25574
OMIM
CCDS CCDS376
HPRD 07697
IMGT
EMBL AK001621 AK122896 AL662907 BC001222 BC007999 BC011689 BC012152 CH471059
GenPept AAH01222 AAH07999 AAH11689 AAH12152 BAA91792 BAG53787 CAH70402 EAX07466 EAX07467
RNA Seq Atlas 55223