|Homo sapiens Gene: TBPL1|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||TBP-like 1|
|Synonyms||MGC:8389; MGC:9620; STUD; TLF; TLP; TRF2;|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011]
|Genomic Location||Chromosome 6:133952170-133990432|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Basal transcription factors pathway
Huntington's disease pathway
|UniProt Splice Variant|
|RNA Seq Atlas|