Version 5.4
Homo sapiens Gene: HYI
Summary
InnateDB Gene IDBG-97471.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HYI
Gene Name hydroxypyruvate isomerase (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178922
Encoded Proteins
IDBP-97473
hydroxypyruvate isomerase (putative)
IDBP-97475
hydroxypyruvate isomerase (putative)
IDBP-97477
hydroxypyruvate isomerase (putative)
IDBP-97479
hydroxypyruvate isomerase (putative)
IDBP-97487
hydroxypyruvate isomerase (putative)
IDBP-480679
hydroxypyruvate isomerase (putative)
IDBP-484554
hydroxypyruvate isomerase (putative)
IDBP-479117
hydroxypyruvate isomerase (putative)
IDBP-721862
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a putative hydroxypyruvate isomerase, which likely catalyzes the conversion of hydroxypyruvate to 2-hydroxy-3-oxopropanoate, and may be involved in carbohydrate transport and metabolism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:43451003-43453989
Strand Reverse strand
Band p34.2
Transcripts
ENST00000372434 ENSP00000361511
ENST00000372433 ENSP00000361510
ENST00000372432 ENSP00000361509
ENST00000372430 ENSP00000361507
ENST00000372427
ENST00000372425 ENSP00000361502
ENST00000483618
ENST00000470662 ENSP00000428803
ENST00000487366 ENSP00000428501
ENST00000486909 ENSP00000428399
ENST00000496142
ENST00000469587
ENST00000583037 ENSP00000461969
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008903 hydroxypyruvate isomerase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006395
View Gene Order
ENSBTAG00000005583
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00630
Glyoxylate and dicarboxylate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6UJY1 Q5T015
UniProt Splice Variant
Entrez Gene 81888
UniGene Hs.709864 Hs.736551
RefSeq NM_001190880 NM_001243526 NM_031207 XM_005271240
HUGO HGNC:26948
OMIM
CCDS CCDS488 CCDS53309 CCDS72771
HPRD 11039
IMGT
EMBL AL583862
GenPept
RNA Seq Atlas 81888

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca