Version 5.4
Homo sapiens Protein: HYI
Summary
InnateDB Protein IDBP-721862.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HYI
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000461969
InnateDB Gene IDBG-97471 (HYI)
Protein Structure
UniProt Annotation
Function Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008903 hydroxypyruvate isomerase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR013022 Xylose isomerase-like, TIM barrel domain
PFAM PF01261
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5T013
PhosphoSite PhosphoSite-Q5T013
TrEMBL
UniProt Splice Variant
Entrez Gene 81888
UniGene Hs.736551
RefSeq NP_001230455
HUGO HGNC:26948
OMIM
CCDS CCDS72771
HPRD 11039
IMGT
EMBL AF284750 AF284751 AL583862 AY037165 AY775560 BC006140 BC019041 CH471059
GenPept AAG59852 AAG59853 AAH06140 AAH19041 AAK67642 AAV84474 CAI14890 CAI14893 EAX07090 EAX07091 EAX07093 EAX07094

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca