Homo sapiens Gene: TSPAN1
Summary
InnateDB Gene IDBG-98081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN1
Gene Name tetraspanin 1
Synonyms NET1; TM4C; TM4SF
Species Homo sapiens
Ensembl Gene ENSG00000117472
Encoded Proteins
tetraspanin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:46175073-46185958
Strand Forward strand
Band p34.1
Transcripts
ENST00000372003 ENSP00000361072
ENST00000498443
ENST00000482928
ENST00000469330
ENST00000475163
ENST00000464786
ENST00000482143
ENST00000472170
ENST00000470318
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015403 thiamine uptake transmembrane transporter activity
Biological Process
GO:0008283 cell proliferation
GO:0016477 cell migration
GO:0045807 positive regulation of endocytosis
GO:0050821 protein stabilization
GO:0071934 thiamine transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031982 vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.38972
RefSeq NM_005727
HUGO
OMIM
CCDS CCDS530
HPRD 18232
IMGT
EMBL
GenPept
RNA Seq Atlas