Homo sapiens Gene: FAAH
Summary
InnateDB Gene IDBG-98116.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAAH
Gene Name fatty acid amide hydrolase
Synonyms FAAH-1; PSAB;
Species Homo sapiens
Ensembl Gene ENSG00000117480
Encoded Proteins
fatty acid amide hydrolase
fatty acid amide hydrolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:46394265-46413848
Strand Forward strand
Band p33
Transcripts
ENST00000243167 ENSP00000243167
ENST00000468718
ENST00000493735
ENST00000484697 ENSP00000481641
ENST00000489366
ENST00000493636
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor
GO:0017064 fatty acid amide hydrolase activity
GO:0047372 acylglycerol lipase activity
Biological Process
GO:0009062 fatty acid catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0012505 endomembrane system
GO:0016021 integral component of membrane
GO:0031090 organelle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
Metabolism of anandamide an endogenous cannabinoid [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 2166
UniGene
RefSeq NM_001441
HUGO HGNC:3553
OMIM 602935
CCDS CCDS535
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 2166