Version 5.4
Homo sapiens Gene: GPX7
Summary
InnateDB Gene IDBG-98647.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPX7
Gene Name glutathione peroxidase 7
Synonyms CL683; GPx-7; GPX6; GSHPx-7; NPGPx
Species Homo sapiens
Ensembl Gene ENSG00000116157
Encoded Proteins
IDBP-98649
glutathione peroxidase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:52602372-52609051
Strand Forward strand
Band p32.3
Transcripts
ENST00000361314 ENSP00000354677
ENST00000459779
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028597
View Gene Order
ENSBTAG00000018281
Not yet available
Pathways
NETPATH
REACTOME
REACT_120956
Cellular responses to stress pathway
REACT_172715
Detoxification of Reactive Oxygen Species pathway
KEGG
hsa00590
Arachidonic acid metabolism pathway
hsa00480
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q96SL4
TrEMBL
UniProt Splice Variant
Entrez Gene 2882
UniGene Hs.43728
RefSeq NM_015696
HUGO HGNC:4559
OMIM 615784
CCDS CCDS569
HPRD
IMGT
EMBL AF091092 AF320068 AK027683 AL356976 AY358402 BC032788 DQ096732
GenPept AAC72961 AAH32788 AAN76501 AAQ88768 AAY88741 BAB55294 CAI22476
RNA Seq Atlas 2882

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca