Version 5.4
Homo sapiens Gene: RNASET2
Summary
InnateDB Gene IDBG-98984.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNASET2
Gene Name ribonuclease T2
Synonyms bA514O12.3; RNASE6PL
Species Homo sapiens
Ensembl Gene ENSG00000026297
Encoded Proteins
IDBP-98986
ribonuclease T2
IDBP-478811
ribonuclease T2
IDBP-388258
ribonuclease T2
IDBP-482154
ribonuclease T2
IDBP-476634
ribonuclease T2
IDBP-477930
ribonuclease T2
IDBP-813699
ribonuclease T2
IDBP-813700
ribonuclease T2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:166929504-166957191
Strand Reverse strand
Band q27
Transcripts
ENST00000028008 ENSP00000028008
ENST00000358165
ENST00000366855 ENSP00000424947
ENST00000421787 ENSP00000390833
ENST00000508775 ENSP00000426455
ENST00000510083
ENST00000476238 ENSP00000422846
ENST00000478180 ENSP00000426059
ENST00000467705
ENST00000499370
ENST00000496851
ENST00000509073
ENST00000611959 ENSP00000480244
ENST00000620173 ENSP00000482755
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004540 ribonuclease activity
GO:0033897 ribonuclease T2 activity
Biological Process
GO:0006401 RNA catabolic process
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005788 endoplasmic reticulum lumen
GO:0043202 lysosomal lumen
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Bos taurus
Mus musculus
Gene ID
Gene Order
ENSBTAG00000014494
Not yet available
ENSMUSG00000095687
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.529989
RefSeq NM_003730
HUGO
OMIM
CCDS CCDS5295
HPRD 10197
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca