Version 5.4
Homo sapiens Gene: PARS2
Summary
InnateDB Gene IDBG-99041.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PARS2
Gene Name prolyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms MT-PRORS
Species Homo sapiens
Ensembl Gene ENSG00000162396
Encoded Proteins
IDBP-99043
prolyl-tRNA synthetase 2, mitochondrial (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:54756898-54764514
Strand Reverse strand
Band p32.3
Transcripts
ENST00000371279 ENSP00000360327
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006433 prolyl-tRNA aminoacylation
GO:0010467 gene expression
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043572
View Gene Order
ENSBTAG00000040313
Not yet available
Pathways
NETPATH
REACTOME
REACT_15302
Mitochondrial tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
hsa00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q7L3T8
TrEMBL
UniProt Splice Variant
Entrez Gene 25973
UniGene Hs.380169
RefSeq NM_152268
HUGO HGNC:30563
OMIM 612036
CCDS CCDS597
HPRD
IMGT
EMBL AK025585 AK289679 AL117473 AL139244 BC007956 BC011758 CH471059
GenPept AAH07956 AAH11758 BAB15178 BAF82368 CAB55948 CAI18996 EAX06669
RNA Seq Atlas 25973

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca