Homo sapiens Gene: TNNI3K
Summary
InnateDB Gene IDBG-99714.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNNI3K
Gene Name TNNI3 interacting kinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116783
Encoded Proteins
FPGT-TNNI3K readthrough
FPGT-TNNI3K readthrough
FPGT-TNNI3K readthrough
FPGT-TNNI3K readthrough
FPGT-TNNI3K readthrough
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription from the neighboring fucose-1-phosphate guanylyltransferase (FPGT) and TNNI3 interacting kinase (TNNI3K) genes. Alternative splicing results in multiple transcript variants that are composed of in-frame exons from each individual gene. [provided by RefSeq, Dec 2010] This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:74235401-74544428
Strand Forward strand
Band p31.1
Transcripts
ENST00000370893 ENSP00000359930
ENST00000326637 ENSP00000322251
ENST00000370889
ENST00000497284
ENST00000465473
ENST00000533006
ENST00000530184
ENST00000526236 ENSP00000431465
ENST00000534020 ENSP00000434975
ENST00000525480 ENSP00000433550
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0031013 troponin I binding
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.662607
RefSeq NM_001112808 NM_001199327 NM_015978
HUGO
OMIM
CCDS CCDS44161 CCDS664
HPRD 18208
IMGT
EMBL
GenPept
RNA Seq Atlas