Version 5.4
Homo sapiens Protein: TNNI3K
Summary
InnateDB Protein IDBP-99728.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNNI3K
Protein Name FPGT-TNNI3K readthrough
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000322251
InnateDB Gene IDBG-99714 (TNNI3K)
Protein Structure
UniProt Annotation
Function May play a role in cardiac physiology. {ECO:0000303PubMed:12721663}.
Subcellular Localization Nucleus {ECO:0000269PubMed:12721663}. Cytoplasm {ECO:0000269PubMed:12721663}. Note=Expressed at lower levels in the cytoplasm.
Disease Associations
Tissue Specificity Highly expressed in both adult and fetal heart. {ECO:0000269PubMed:12721663}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0031013 troponin I binding
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002110 Ankyrin repeat
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
IPR020683 Ankyrin repeat-containing domain
PFAM PF00069
PF07714
PF00023
PF13606
PF11929
PF12796
PRINTS PR00109
PR01415
PIRSF
SMART SM00248
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q59H18
PhosphoSite PhosphoSite-Q59H18
TrEMBL
UniProt Splice Variant
Entrez Gene 51086
UniGene Hs.662607
RefSeq NP_057062
HUGO HGNC:19661
OMIM 613932
CCDS CCDS664
HPRD 18208
IMGT
EMBL AB208941 AC093158 AC098692 AC105271 AC119672 AF116826 AY303691 BC032865 BC113539 BC117262 BX470253 BX640903 CH471059 DQ822519
GenPept AAD29632 AAH32865 AAI13540 AAI17263 AAP72030 ABG46944 BAD92178 CAE45949 CAI16293 EAX06415

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca