InnateDB Protein
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IDBP-101569.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FCGR1B
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Protein Name
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Fc fragment of IgG, high affinity Ib, receptor (CD64)
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Synonyms
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CD64b; IGFRB;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000358390
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InnateDB Gene
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IDBG-101565 (FCGR1B)
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Protein Structure
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Function |
May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response. {ECO:0000269PubMed:1430234, ECO:0000269PubMed:9881690}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:1430234}; Single-pass type I membrane protein {ECO:0000269PubMed:1430234}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
GO:0002474
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antigen processing and presentation of peptide antigen via MHC class I
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GO:0002479
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antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
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GO:0006955
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immune response
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GO:0019221
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cytokine-mediated signaling pathway
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GO:0038093
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Fc receptor signaling pathway
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GO:0042590
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antigen processing and presentation of exogenous peptide antigen via MHC class I
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GO:0060333
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interferon-gamma-mediated signaling pathway
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Cellular Component |
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PDB ID |
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InterPro |
IPR007110
Immunoglobulin-like domain
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q92637
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PhosphoSite |
PhosphoSite-Q92637
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
2210
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UniGene |
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RefSeq |
NP_001004340
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HUGO |
HGNC:3614
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OMIM |
601503
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CCDS |
CCDS72846
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HPRD |
14225
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IMGT |
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EMBL |
AL357493
L03419
L03420
S45704
S45705
S45707
S45708
S45709
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GenPept |
AAA35825
AAA35826
AAD13842
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