InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FMO5

Summary

InnateDB Protein

IDBP-101811.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FMO5

Protein Name

flavin containing monooxygenase 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000254090

InnateDB Gene

IDBG-101809 (FMO5)

Protein Structure

UniProt Annotation

Function

In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.

Subcellular Localization

Microsome membrane. Endoplasmic reticulum membrane.

Disease Associations

Tissue Specificity

Expressed in fetal and adult liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0016491	oxidoreductase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

Biological Process

GO:0008150	biological_process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000960 Flavin monooxygenase FMO
IPR002253 Flavin monooxygenase (FMO) 1
IPR002254 Flavin monooxygenase (FMO) 2
IPR002257 Flavin monooxygenase (FMO) 5
IPR012143 Dimethylaniline monooxygenase, N-oxide-forming
IPR020946 Flavin monooxygenase-like
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM

PF00743
PF07992

PRINTS

PR00370
PR01121
PR01122
PR01125

PIRSF

PIRSF000332

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt