Homo sapiens Protein: ZFP36L1
Summary
InnateDB Protein IDBP-10191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZFP36L1
Protein Name zinc finger protein 36, C3H type-like 1
Synonyms Berg36; BRF1; cMG1; ERF-1; ERF1; RNF162B; TIS11B;
Species Homo sapiens
Ensembl Protein ENSP00000337386
InnateDB Gene IDBG-10189 (ZFP36L1)
Protein Structure
UniProt Annotation
Function Probable regulatory protein involved in regulating the response to growth factors.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0043488 regulation of mRNA stability
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000571 Zinc finger, CCCH-type
IPR007635 Tis11B-like protein, N-terminal
PFAM PF00642
PF04553
PRINTS
PIRSF
SMART SM00356
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q07352
PhosphoSite PhosphoSite-Q07352
TrEMBL G3V2D5
UniProt Splice Variant
Entrez Gene 677
UniGene Hs.85155
RefSeq
HUGO HGNC:1107
OMIM 601064
CCDS CCDS9791
HPRD 03041
IMGT
EMBL AK294363 AK303917 AL132986 BC018340 BT019468 CH471061 X79066 X79067 X99404
GenPept AAH18340 AAV38275 BAG57626 BAG64845 CAA55670 CAA67781 EAW80967 EAW80968