Version 5.4
Homo sapiens Protein: S100A1
Summary
InnateDB Protein IDBP-102743.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100A1
Protein Name S100 calcium binding protein A1
Synonyms S100; S100-alpha; S100A;
Species Homo sapiens
Ensembl Protein ENSP00000357687
InnateDB Gene IDBG-102741 (S100A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044548 S100 protein binding
GO:0051117 ATPase binding
Biological Process
GO:0008016 regulation of heart contraction
GO:0021762 substantia nigra development
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005634 nucleus
GO:0016529 sarcoplasmic reticulum
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF00036
PF13202
PF13405
PF01023
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5T7Y6
UniProt Splice Variant
Entrez Gene 6271
UniGene
RefSeq
HUGO HGNC:10486
OMIM 176940
CCDS
HPRD 01489
IMGT
EMBL AB451316 AB451446 AK312152 AL162258 BC014392 BT006938 CH471121 X58079
GenPept AAH14392 AAP35584 BAG35086 BAG70130 BAG70260 CAA41107 CAI19677 EAW53301 EAW53302

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca