InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RUSC1

Summary

InnateDB Protein

IDBP-103257.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RUSC1

Protein Name

RUN and SH3 domain containing 1

Synonyms

NESCA;

Species

Homo sapiens

Ensembl Protein

ENSP00000357331

InnateDB Gene

IDBG-103247 (RUSC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005070	SH3/SH2 adaptor activity
GO:0005515	protein binding

Biological Process

GO:0000209	protein polyubiquitination
GO:0009967	positive regulation of signal transduction
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005769	early endosome
GO:0005794	Golgi apparatus
GO:0005874	microtubule
GO:0014069	postsynaptic density
GO:0015630	microtubule cytoskeleton
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030054	cell junction
GO:0031410	cytoplasmic vesicle
GO:0045211	postsynaptic membrane