Homo sapiens Protein: HDGF
Summary
InnateDB Protein IDBP-103616.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HDGF
Protein Name hepatoma-derived growth factor
Synonyms HMG1L2;
Species Homo sapiens
Ensembl Protein ENSP00000357189
InnateDB Gene IDBG-103610 (HDGF)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 203 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 203 [view]
Protein-Protein 203 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0001106 RNA polymerase II transcription corepressor activity
GO:0001222 transcription corepressor binding
GO:0003677 DNA binding
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0007165 signal transduction
GO:0008283 cell proliferation
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR000313 PWWP domain
PFAM PF00855
PRINTS
PIRSF
SMART SM00293
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51858
PhosphoSite PhosphoSite-P51858
TrEMBL A8K8G0
UniProt Splice Variant
Entrez Gene 3068
UniGene Hs.506748
RefSeq NP_001119522
HUGO HGNC:4856
OMIM 600339
CCDS CCDS44247
HPRD 02079
IMGT
EMBL AK096411 AK292325 AL590666 BC018991 CH471121 D16431
GenPept AAH18991 BAA03903 BAF85014 BAG53283 EAW52910 EAW52911 EAW52912