InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRMT1L

Summary

InnateDB Protein

IDBP-105376.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRMT1L

Protein Name

TRM1 tRNA methyltransferase 1-like

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000356476

InnateDB Gene

IDBG-105374 (TRMT1L)

Protein Structure

UniProt Annotation

Function

May play a role in motor coordination and exploratory behavior. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Widely expressed. {ECO:0000269PubMed:11318611}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
GO:0016740	transferase activity
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0008033	tRNA processing
GO:0008344	adult locomotory behavior
GO:0030488	tRNA methylation
GO:0030534	adult behavior

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR002905 tRNA methyltransferase, Trm1
IPR003402 tRNA transferase Trm5/Tyw2
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF02005
PF02475
PF00096

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7Z2T5