Homo sapiens Gene: TRMT1L
Summary
InnateDB Gene IDBG-105374.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRMT1L
Gene Name tRNA methyltransferase 1 homolog (S. cerevisiae)-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000121486
Encoded Proteins
TRM1 tRNA methyltransferase 1-like
TRM1 tRNA methyltransferase 1-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:185118098-185157072
Strand Reverse strand
Band q25.3
Transcripts
ENST00000367506 ENSP00000356476
ENST00000458395 ENSP00000414339
ENST00000465827
ENST00000487028
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity
GO:0016740 transferase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0008033 tRNA processing
GO:0008344 adult locomotory behavior
GO:0030488 tRNA methylation
GO:0030534 adult behavior
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL X6RK96
UniProt Splice Variant
Entrez Gene 81627
UniGene Hs.107149 Hs.602943 Hs.719468
RefSeq NM_001202423 NM_030934
HUGO HGNC:16782
OMIM 611673
CCDS CCDS1366
HPRD 12722
IMGT
EMBL AL109865 AL136133
GenPept
RNA Seq Atlas 81627