InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LDB2

Summary

InnateDB Protein

IDBP-10854.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LDB2

Protein Name

LIM domain binding 2

Synonyms

CLIM1; LDB1;

Species

Homo sapiens

Ensembl Protein

ENSP00000306772

InnateDB Gene

IDBG-10850 (LDB2)

Protein Structure

UniProt Annotation

Function

Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors.

Subcellular Localization

Nucleus {ECO:0000269PubMed:9853615}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	17 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000989	transcription factor binding transcription factor activity
GO:0003712	transcription cofactor activity
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0030274	LIM domain binding

Biological Process

GO:0001942	hair follicle development
GO:0010669	epithelial structure maintenance
GO:0035019	somatic stem cell maintenance
GO:0044089	positive regulation of cellular component biogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter