InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vps41

Summary

InnateDB Protein

IDBP-132228.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vps41

Protein Name

vacuolar protein sorting 41 (yeast)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000072729

InnateDB Gene

IDBG-132226 (Vps41)

Protein Structure

UniProt Annotation

Function

Required for vacuolar assembly and vacuolar traffic. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0008270	zinc ion binding

Biological Process

GO:0006886	intracellular protein transport
GO:0016192	vesicle-mediated transport
GO:0048193	Golgi vesicle transport

Cellular Component

GO:0005765	lysosomal membrane
GO:0005769	early endosome
GO:0005770	late endosome
GO:0005798	Golgi-associated vesicle
GO:0005829	cytosol
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane
GO:0030897	HOPS complex

Protein Structure and Domains

PDB ID

MGI:1929215

InterPro

IPR000547 Clathrin, heavy chain/VPS, 7-fold repeat
IPR001841 Zinc finger, RING-type
IPR016024 Armadillo-type fold
IPR016902 Vacuolar protein sorting-associated protein 41
IPR017986 WD40-repeat-containing domain

PFAM

PF00637
PF13639
PF14634

PRINTS

PIRSF

PIRSF028921

SMART

SM00299
SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt