Version 5.4
Mus musculus Protein: Nid2
Summary
InnateDB Protein IDBP-134021.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nid2
Protein Name nidogen 2
Synonyms AW547149; entactin-2; Ly111; NID-2; nidogen-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000022340
InnateDB Gene IDBG-134019 (Nid2)
Protein Structure
UniProt Annotation
Function Cell adhesion glycoprotein. Might be involved in osteoblast differentiation. It probably has a role in cell- extracellular matrix interactions.
Subcellular Localization Secreted, extracellular space, extracellular matrix, basement membrane.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007160 cell-matrix adhesion
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0009986 cell surface
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1298229
InterPro IPR000033 LDLR class B repeat
IPR000716 Thyroglobulin type-1
IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR003886 Nidogen, extracellular domain
IPR006605 G2 nidogen/fibulin G2F
IPR009017 Green fluorescent protein
PFAM PF00058
PF00086
PF00008
PF07645
PF06119
PF07474
PRINTS
PIRSF
SMART SM00135
SM00211
SM00181
SM00179
SM00539
SM00682
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88322
PhosphoSite PhosphoSite-O88322
TrEMBL
UniProt Splice Variant
Entrez Gene 18074
UniGene Mm.471358
RefSeq NP_032721
MGI ID
MGI Symbol Nid2
OMIM
CCDS CCDS36813
HPRD
IMGT
EMBL AB017202 BC054746 BC057016 CH466613
GenPept AAH54746 AAH57016 BAA32609 EDL01537

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca