Version 5.4
Mus musculus Gene: Nid2
Summary
InnateDB Gene IDBG-134019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nid2
Gene Name nidogen 2
Synonyms AW547149; entactin-2; Ly111; NID-2; nidogen-2
Species Mus musculus
Ensembl Gene ENSMUSG00000021806
Encoded Proteins
IDBP-134021
nidogen 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087303:
This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.[provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:19751257-19811787
Strand Forward strand
Band A3
Transcripts
ENSMUST00000022340 ENSMUSP00000022340
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007160 cell-matrix adhesion
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
GO:0009986 cell surface
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000087303
View Gene Order
ENSBTAG00000021945
Not yet available
Pathways
NETPATH
REACTOME
REACT_206066
Extracellular matrix organization pathway
REACT_202342
Laminin interactions pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118779
Extracellular matrix organization pathway
REACT_169262
Laminin interactions pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O88322
TrEMBL
UniProt Splice Variant
Entrez Gene 18074
UniGene Mm.471358
RefSeq NM_008695
OMIM
CCDS CCDS36813
HPRD
IMGT
MGI ID MGI:1298229
MGI Symbol Nid2
EMBL AB017202 BC054746 BC057016 CH466613
GenPept AAH54746 AAH57016 BAA32609 EDL01537
RNA Seq Atlas 18074

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca