Mus musculus Protein: Proz | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-134383.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Proz | ||||||||||
Protein Name | protein Z, vitamin K-dependent plasma glycoprotein | ||||||||||
Synonyms | 1300015B06Rik; | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000033822 | ||||||||||
InnateDB Gene | IDBG-134381 (Proz) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Secreted. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | Plasma. | ||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | MGI:1860488 | ||||||||||
InterPro |
IPR000294
Gamma-carboxyglutamic acid-rich (GLA) domain IPR000742 Epidermal growth factor-like domain IPR001254 Peptidase S1 IPR001881 EGF-like calcium-binding domain IPR009003 Trypsin-like cysteine/serine peptidase domain IPR012224 Peptidase S1A, coagulation factor VII/IX/X/C/Z |
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PFAM |
PF00594
PF00008 PF00089 PF07645 |
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PRINTS |
PR00001
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PIRSF |
PIRSF001143
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SMART |
SM00069
SM00181 SM00020 SM00179 |
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q9CQW3 | ||||||||||
PhosphoSite | PhosphoSite- | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 66901 | ||||||||||
UniGene | Mm.441140 | ||||||||||
RefSeq | NP_080110 | ||||||||||
MGI ID | |||||||||||
MGI Symbol | Proz | ||||||||||
OMIM | |||||||||||
CCDS | CCDS22105 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AK005011 AK008819 | ||||||||||
GenPept | BAB25912 | ||||||||||