Version 5.4
Mus musculus Protein: Akr1b8
Summary
InnateDB Protein IDBP-134637.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Akr1b8
Protein Name aldo-keto reductase family 1, member B8
Synonyms Fgfrp; Fgrp; FR-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000040244
InnateDB Gene IDBG-134635 (Akr1b8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:107673
InterPro IPR020471 Aldo/keto reductase subgroup
IPR023210 NADP-dependent oxidoreductase domain
PFAM PF00248
PRINTS PR00069
PIRSF PIRSF000097
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P45377
PhosphoSite PhosphoSite-P45377
TrEMBL
UniProt Splice Variant
Entrez Gene 14187
UniGene Mm.5378
RefSeq NP_032038
MGI ID 1FRB
MGI Symbol Akr1b8
OMIM
CCDS CCDS19991
HPRD
IMGT
EMBL BC005789 U04204
GenPept AAA16953 AAH05789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca