InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ifngr1

Summary

InnateDB Protein

IDBP-135938.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ifngr1

Protein Name

interferon gamma receptor 1

Synonyms

CD119; Ifgr; IFN-gammaR; Ifngr; Nktar;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020188

InnateDB Gene

IDBG-135936 (Ifngr1)

Protein Structure

UniProt Annotation

Function

Receptor for interferon gamma. Two receptors bind one interferon gamma dimer.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019955	cytokine binding

Biological Process

GO:0045087

innate immune response (InnateDB)

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030425	dendrite
GO:0031982	vesicle

Protein Structure and Domains

PDB ID

MGI:107655

InterPro

IPR003961 Fibronectin, type III
IPR008355 Interferon gamma receptor alpha subunit
IPR015373 Interferon alpha/beta receptor, beta chain
IPR021126 Interferon gamma receptor, poxvirus/mammal

PFAM

PF00041
PF01108
PF09294
PF07140

PRINTS

PR01777

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt