InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hfe

Summary

InnateDB Protein

IDBP-136759.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Hfe

Protein Name

hemochromatosis

Synonyms

MR2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000006787

InnateDB Gene

IDBG-136751 (Hfe)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003823	antigen binding
GO:0005102	receptor binding
GO:0005515	protein binding

Biological Process

GO:0019882	antigen processing and presentation
GO:0042446	hormone biosynthetic process
GO:0055072	iron ion homeostasis
GO:0060586	multicellular organismal iron ion homeostasis
GO:0097459	iron ion import into cell

Cellular Component

GO:0005886

plasma membrane

Protein Structure and Domains

PDB ID

MGI:109191

InterPro

IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain

PFAM

PF07654

PRINTS

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5SZ91

UniProt Splice Variant

Entrez Gene

15216

UniGene

Mm.487725

RefSeq

MGI ID

MGI Symbol

Hfe

OMIM

CCDS

HPRD

IMGT

EMBL

AL590388 AL592149

GenPept