Version 5.4
Mus musculus Protein: Aqp7
Summary
InnateDB Protein IDBP-136955.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp7
Protein Name aquaporin 7
Synonyms AQP7L; AQPap;
Species Mus musculus
Ensembl Protein ENSMUSP00000030136
InnateDB Gene IDBG-136953 (Aqp7)
Protein Structure
UniProt Annotation
Function Forms a channel for water and glycerol.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015250 water channel activity
GO:0015254 glycerol channel activity
GO:0015265 urea channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0007283 spermatogenesis
GO:0015793 glycerol transport
GO:0015840 urea transport
GO:0042493 response to drug
GO:0070295 renal water absorption
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
GO:0031526 brush border membrane
Protein Structure and Domains
PDB ID MGI:1314647
InterPro IPR000425 Major intrinsic protein
IPR023271 Aquaporin-like
PFAM PF00230
PRINTS PR00783
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O54794
PhosphoSite PhosphoSite-
TrEMBL Q5DX24
UniProt Splice Variant
Entrez Gene 11832
UniGene Mm.8728
RefSeq NP_031499
MGI ID
MGI Symbol Aqp7
OMIM
CCDS CCDS18055
HPRD
IMGT
EMBL AB010100 AB027516 AB056091 AB056099 AK076642 AK131744 BC022223 CH466538
GenPept AAH22223 BAA24537 BAB40312 BAB68537 BAB68540 BAC36431 BAE20793 EDL05417

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca