InnateDB Protein
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IDBP-139626.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Alg11
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Protein Name
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asparagine-linked glycosylation 11 homolog (yeast, alpha-1,2-mannosyltransferase)
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000072382
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InnateDB Gene
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IDBG-139624 (Alg11)
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Protein Structure
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Function |
Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003674
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molecular_function
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GO:0004377
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GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2142632
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InterPro |
IPR001296
Glycosyl transferase, family 1
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PFAM |
PF00534
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3TZM9
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PhosphoSite |
PhosphoSite-Q3TZM9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
207958
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UniGene |
Mm.489240
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RefSeq |
NP_001230090
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MGI ID |
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MGI Symbol |
Alg11
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OMIM |
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CCDS |
CCDS57613
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HPRD |
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IMGT |
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EMBL |
AK046475
AK157746
BC061469
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GenPept |
AAH61469
BAC32746
BAE34179
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