InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MAPK8IP2

Summary

InnateDB Protein

IDBP-14070.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MAPK8IP2

Protein Name

mitogen-activated protein kinase 8 interacting protein 2

Synonyms

IB-2; IB2; JIP2; PRKM8IPL;

Species

Homo sapiens

Ensembl Protein

ENSP00000330572

InnateDB Gene

IDBG-14068 (MAPK8IP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 95 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	95 [view]
Protein-Protein	93 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001540	beta-amyloid binding
GO:0005078	MAP-kinase scaffold activity
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0019894	kinesin binding
GO:0019901	protein kinase binding
GO:0030295	protein kinase activator activity
GO:0032403	protein complex binding

Biological Process

GO:0000165	MAPK cascade
GO:0001662	behavioral fear response
GO:0007172	signal complex assembly
GO:0007254	JNK cascade
GO:0007617	mating behavior
GO:0009967	positive regulation of signal transduction
GO:0010469	regulation of receptor activity
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0035176	social behavior
GO:0045860	positive regulation of protein kinase activity
GO:0046328	regulation of JNK cascade
GO:0046958	nonassociative learning
GO:0048813	dendrite morphogenesis
GO:0051966	regulation of synaptic transmission, glutamatergic
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity