Version 5.4
Mus musculus Protein: Diap1
Summary
InnateDB Protein IDBP-140707.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Diap1
Protein Name diaphanous homolog 1 (Drosophila)
Synonyms D18Wsu154e; Dia1; Diaph1; Drf1; mKIAA4062; p140mDia;
Species Mus musculus
Ensembl Protein ENSMUSP00000078942
InnateDB Gene IDBG-140703 (Diap1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 32 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
Cellular Component
GO:0032587 ruffle membrane
Protein Structure and Domains
PDB ID MGI:1194490
InterPro IPR009408 Formin Homology 1
IPR010465 DRF autoregulatory
IPR010472 Formin, FH3 domain
IPR010473 Formin, GTPase-binding domain
IPR015425 Formin, FH2 domain
IPR016024 Armadillo-type fold
PFAM PF06346
PF06345
PF06367
PF06371
PF02181
PRINTS
PIRSF
SMART SM00498
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9CSJ1
UniProt Splice Variant
Entrez Gene 13367
UniGene Mm.401799
RefSeq
MGI ID
MGI Symbol Diap1
OMIM
CCDS
HPRD
IMGT
EMBL AC129315 AK012707 AK135915
GenPept BAB28425 BAE22723

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca