InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lama2

Summary

InnateDB Protein

IDBP-140722.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Lama2

Protein Name

laminin, alpha 2

Synonyms

5830440B04; dy; mer; merosin; mKIAA4087;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000090304

InnateDB Gene

IDBG-140720 (Lama2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007411	axon guidance
GO:0016192	vesicle-mediated transport
GO:0022011	myelination in peripheral nervous system
GO:0030155	regulation of cell adhesion
GO:0030198	extracellular matrix organization
GO:0030334	regulation of cell migration
GO:0032224	positive regulation of synaptic transmission, cholinergic
GO:0045995	regulation of embryonic development

Cellular Component

GO:0005576	extracellular region
GO:0005604	basement membrane
GO:0005605	basal lamina
GO:0005606	laminin-1 complex
GO:0016020	membrane
GO:0042383	sarcolemma
GO:0043197	dendritic spine
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:99912

InterPro

IPR000034 Laminin B type IV
IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR002049 EGF-like, laminin
IPR008211 Laminin, N-terminal
IPR008979 Galactose-binding domain-like
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR009254 Laminin I
IPR010307 Laminin II
IPR010989 t-SNARE
IPR018031 Laminin B, subgroup
IPR029048 Heat shock protein 70kD, C-terminal domain

PFAM