Homo sapiens Protein: C1QTNF3
Summary
InnateDB Protein IDBP-15031.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C1QTNF3
Protein Name C1q and tumor necrosis factor related protein 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000371497
InnateDB Gene IDBG-15015 (C1QTNF3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in colon and small intestine. {ECO:0000269PubMed:14654242}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0010629 negative regulation of gene expression
GO:0035356 cellular triglyceride homeostasis
GO:0042347 negative regulation of NF-kappaB import into nucleus
GO:0045087 innate immune response (InnateDB)
GO:0045444 fat cell differentiation
GO:0045721 negative regulation of gluconeogenesis
GO:0050715 positive regulation of cytokine secretion
GO:0050728 negative regulation of inflammatory response
GO:0070165 positive regulation of adiponectin secretion
GO:0070206 protein trimerization
GO:0071638 negative regulation of monocyte chemotactic protein-1 production
GO:1900165 negative regulation of interleukin-6 secretion
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001073 Complement C1q protein
IPR008160 Collagen triple helix repeat
IPR008983 Tumour necrosis factor-like domain
PFAM PF00386
PF01391
PRINTS PR00007
PIRSF
SMART SM00110
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BXJ4
PhosphoSite PhosphoSite-Q9BXJ4
TrEMBL
UniProt Splice Variant
Entrez Gene 114899
UniGene Hs.605266
RefSeq NP_852100
HUGO HGNC:14326
OMIM 612045
CCDS CCDS34141
HPRD 12716
IMGT
EMBL AC139783 AC139792 AF173888 AF326976 AF329837 AK075533 AK295968 AK315921 AY358388 BC112925 BC120990 BX640995 CH471118 EU399231 EU399232
GenPept AAI12926 AAI20991 AAK17961 AAK70344 AAQ13635 AAQ88754 ABY86416 ABY86417 BAC11676 BAG58744 BAH14292 CAE45998 EAX10820