Version 5.4
Mus musculus Protein: Ugcg
Summary
InnateDB Protein IDBP-151203.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ugcg
Protein Name UDP-glucose ceramide glucosyltransferase
Synonyms AU043821; C80537; Epcs21; GlcT-1; Ugcgl;
Species Mus musculus
Ensembl Protein ENSMUSP00000030074
InnateDB Gene IDBG-151201 (Ugcg)
Protein Structure
UniProt Annotation
Function Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase" (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008120 ceramide glucosyltransferase activity
Biological Process
GO:0006665 sphingolipid metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1332243
InterPro IPR001173 Glycosyltransferase 2-like
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF00535
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88693
PhosphoSite PhosphoSite-O88693
TrEMBL
UniProt Splice Variant
Entrez Gene 22234
UniGene Mm.394516
RefSeq NP_035803
MGI ID
MGI Symbol Ugcg
OMIM
CCDS CCDS18219
HPRD
IMGT
EMBL AB012807 AL808112 BC050828 CH466565 D89866
GenPept AAH50828 BAA28782 BAA33558 CAM26180 EDL02214

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca