Version 5.4
Mus musculus Protein: Rod1
Summary
InnateDB Protein IDBP-151325.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rod1
Protein Name ROD1 regulator of differentiation 1 (S. pombe)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000030076
InnateDB Gene IDBG-151323 (Rod1)
Protein Structure
UniProt Annotation
Function RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U) (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0043249 erythrocyte maturation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1923334
InterPro IPR000504 RNA recognition motif domain
IPR006536 HnRNP-L/PTB/hephaestus splicing factor
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BHD7
PhosphoSite PhosphoSite-Q8BHD7
TrEMBL Q8C5Q1
UniProt Splice Variant
Entrez Gene 230257
UniGene Mm.490588
RefSeq NP_835458
MGI ID
MGI Symbol Ptbp3
OMIM
CCDS CCDS18221
HPRD
IMGT
EMBL AK033732 AK077791 AK088560 AL824704 BC006638 BC057641
GenPept AAH06638 AAH57641 BAC28453 BAC37012 BAC40425 CAM19768 CAM19769

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca