Mus musculus Protein: Man1a
Summary
InnateDB Protein IDBP-151746.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Man1a
Protein Name mannosidase 1, alpha
Synonyms Man1a1; PCR1;
Species Mus musculus
Ensembl Protein ENSMUSP00000003843
InnateDB Gene IDBG-151744 (Man1a)
Protein Structure
UniProt Annotation
Function Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Subcellular Localization Golgi apparatus membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:104677
InterPro IPR001382 Glycoside hydrolase, family 47
PFAM PF01532
PRINTS PR00747
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P45700
PhosphoSite PhosphoSite-P45700
TrEMBL Q544T7
UniProt Splice Variant
Entrez Gene 17155
UniGene Mm.408047
RefSeq NP_032574
MGI ID 1NXC
MGI Symbol Man1a
OMIM
CCDS CCDS23848
HPRD
IMGT
EMBL AK031038 AK154820 BC015265 CH466540 U04299
GenPept AAA17747 AAH15265 BAC27225 BAE32852 EDL05098 EDL05100