InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Man1a

Summary

InnateDB Protein

IDBP-151746.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Man1a

Protein Name

mannosidase 1, alpha

Synonyms

Man1a1; PCR1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003843

InnateDB Gene

IDBG-151744 (Man1a)

Protein Structure

UniProt Annotation

Function

Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).

Subcellular Localization

Golgi apparatus membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509	calcium ion binding

Biological Process

GO:0006486

protein glycosylation

Cellular Component

GO:0000139	Golgi membrane
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome