InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tsta3

Summary

InnateDB Protein

IDBP-151938.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tsta3

Protein Name

tissue specific transplantation antigen P35B

Synonyms

AI256181; FX; Tstap35b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023231

InnateDB Gene

IDBG-151936 (Tsta3)

Protein Structure

UniProt Annotation

Function

Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008831	dTDP-4-dehydrorhamnose reductase activity
GO:0016853	isomerase activity
GO:0050577	GDP-L-fucose synthase activity
GO:0050662	coenzyme binding

Biological Process

GO:0019673	GDP-mannose metabolic process
GO:0019835	cytolysis
GO:0042351	'de novo' GDP-L-fucose biosynthetic process
GO:0044237	cellular metabolic process
GO:0045226	extracellular polysaccharide biosynthetic process
GO:0055114	oxidation-reduction process