InnateDB Protein
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IDBP-152075.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Atp6v1d
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Protein Name
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ATPase, H+ transporting, lysosomal V1 subunit D
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Synonyms
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1110004P10Rik; Atp6m; VATD; Vma8;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000021536
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InnateDB Gene
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IDBG-152073 (Atp6v1d)
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Protein Structure
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Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Localizes to centrosome and the base of the cilium. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
21 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0042626
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ATPase activity, coupled to transmembrane movement of substances
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1921084
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InterPro |
IPR002699
ATPase, V1 complex, subunit D
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PFAM |
PF01813
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P57746
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PhosphoSite |
PhosphoSite-P57746
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TrEMBL |
Q9CTI8
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UniProt Splice Variant |
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Entrez Gene |
73834
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UniGene |
Mm.311549
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RefSeq |
NP_076210
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MGI ID |
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MGI Symbol |
Atp6v1d
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OMIM |
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CCDS |
CCDS26002
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HPRD |
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IMGT |
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EMBL |
AF298810
AK003446
AK147910
AK152367
AK165761
BC033457
CH466590
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GenPept |
AAG30225
AAH33457
BAB22795
BAE28222
BAE31157
BAE38369
EDL02626
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