InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gda

Summary

InnateDB Protein

IDBP-152463.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gda

Protein Name

guanine deaminase

Synonyms

AU015411; AW047581;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000084882

InnateDB Gene

IDBG-152459 (Gda)

Protein Structure

UniProt Annotation

Function

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0008892	guanine deaminase activity
GO:0016787	hydrolase activity

Biological Process

GO:0006147

guanine catabolic process

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:95678

InterPro

IPR006680 Amidohydrolase 1
IPR014311 Guanine deaminase

PFAM

PF01979

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9R111

PhosphoSite

PhosphoSite-Q9R111

TrEMBL

Q6DFY1

UniProt Splice Variant

Entrez Gene

14544

UniGene

Mm.45054

RefSeq

NP_034396

MGI ID

MGI Symbol

Gda

OMIM

CCDS

CCDS29698

HPRD

IMGT

EMBL

AC103947 AC125083 AF174583 AF369880 AF369881 AF369882 AK041056 AK173138 BC076583

GenPept

AAD50297 AAH76583 AAM18369 AAM18370 AAM18371 BAC30802 BAD32416