Version 5.4
Mus musculus Gene: Gda
Summary
InnateDB Gene IDBG-152459.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gda
Gene Name guanine deaminase
Synonyms AU015411; AW047581
Species Mus musculus
Ensembl Gene ENSMUSG00000058624
Encoded Proteins
IDBP-152463
guanine deaminase
IDBP-401308
guanine deaminase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119125:
This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:21391307-21473445
Strand Reverse strand
Band B
Transcripts
ENSMUST00000087600 ENSMUSP00000084882
ENSMUST00000121725 ENSMUSP00000112758
ENSMUST00000136258
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008892 guanine deaminase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006147 guanine catabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119125
View Gene Order
ENSBTAG00000011545
Not yet available
Pathways
NETPATH
REACTOME
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_245662
Metabolism of nucleotides pathway
REACT_253802
Purine catabolism pathway
KEGG
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_2086
Purine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt Q9R111
TrEMBL D3YU09 Q548F2 Q69ZN0 Q6DFY1
UniProt Splice Variant
Entrez Gene 14544
UniGene Mm.404200 Mm.412657 Mm.412687 Mm.45054
RefSeq NM_010266 XM_006526680
OMIM
CCDS CCDS29698
HPRD
IMGT
MGI ID MGI:95678
MGI Symbol Gda
EMBL AC103947 AC125083 AF174583 AF369880 AF369881 AF369882 AK041056 AK173138 BC076583
GenPept AAD50297 AAH76583 AAM18369 AAM18370 AAM18371 BAC30802 BAD32416
RNA Seq Atlas 14544

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca