Version 5.4
Mus musculus Protein: Gadd45g
Summary
InnateDB Protein IDBP-152601.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gadd45g
Protein Name growth arrest and DNA-damage-inducible 45 gamma
Synonyms AI327420; C86281; CR6; DDIT2; OIG37;
Species Mus musculus
Ensembl Protein ENSMUSP00000021903
InnateDB Gene IDBG-152599 (Gadd45g)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 53 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000185 activation of MAPKKK activity
GO:0000186 activation of MAPKK activity
GO:0006469 negative regulation of protein kinase activity
GO:0006950 response to stress
GO:0042095 interferon-gamma biosynthetic process
GO:0043065 positive regulation of apoptotic process
GO:0045063 T-helper 1 cell differentiation
GO:0046330 positive regulation of JNK cascade
GO:0051726 regulation of cell cycle
GO:1900745 positive regulation of p38MAPK cascade
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1346325
InterPro IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45
IPR029064 50S ribosomal protein L30e-like
PFAM PF01248
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9R0S0
UniProt Splice Variant
Entrez Gene 23882
UniGene
RefSeq NP_035947
MGI ID
MGI Symbol Gadd45g
OMIM
CCDS CCDS26515
HPRD
IMGT
EMBL AB021884 AC126247 AY258502 CH466546
GenPept AAP79506 BAA78538 EDL41110

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca