InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc6a8

Summary

InnateDB Protein

IDBP-153263.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc6a8

Protein Name

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

Synonyms

AA589632; Creat; CRT; CRTR; CT1; CTR5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033752

InnateDB Gene

IDBG-153261 (Slc6a8)

Protein Structure

UniProt Annotation

Function

Required for the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier.

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005308	creatine transmembrane transporter activity
GO:0005309	creatine:sodium symporter activity
GO:0005328	neurotransmitter:sodium symporter activity
GO:0015220	choline transmembrane transporter activity

Biological Process

GO:0006814	sodium ion transport
GO:0006836	neurotransmitter transport
GO:0015871	choline transport
GO:0015881	creatine transport
GO:1902598	creatine transmembrane transport