Version 5.4
Mus musculus Protein: Idh3g
Summary
InnateDB Protein IDBP-153766.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Idh3g
Protein Name isocitrate dehydrogenase 3 (NAD+), gamma
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000056502
InnateDB Gene IDBG-153764 (Idh3g)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004449 isocitrate dehydrogenase (NAD+) activity
GO:0005524 ATP binding
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0006102 isocitrate metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1099463
InterPro IPR004434 Isocitrate dehydrogenase NAD-dependent
IPR024084 Isopropylmalate dehydrogenase-like domain
PFAM PF00180
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70404
PhosphoSite PhosphoSite-P70404
TrEMBL Q9CW65
UniProt Splice Variant
Entrez Gene 15929
UniGene Mm.14825
RefSeq NP_032349
MGI ID
MGI Symbol Idh3g
OMIM
CCDS CCDS30212
HPRD
IMGT
EMBL AF133093 AJ748655 AK003109 AK156309 AK166925 AK168526 BC085179 BC119170 BC119172 CH466650 U68564
GenPept AAC53340 AAH85179 AAI19171 AAI19173 BAB22571 BAE33665 BAE39120 BAE40405 CAG38689 EDL29879

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca