Version 5.4
Homo sapiens Protein: SPATA13
Summary
InnateDB Protein IDBP-15523.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPATA13
Protein Name spermatogenesis associated 13
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000371542
InnateDB Gene IDBG-15519 (SPATA13)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0030676 Rac guanyl-nucleotide exchange factor activity
Biological Process
GO:0016477 cell migration
GO:0030032 lamellipodium assembly
GO:0030334 regulation of cell migration
GO:0032855 positive regulation of Rac GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0046847 filopodium assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0032587 ruffle membrane
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR011511 Variant SH3 domain
PFAM PF00621
PF00018
PF14604
PF00169
PF07653
PRINTS PR00452
PIRSF
SMART SM00325
SM00326
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96N96
PhosphoSite PhosphoSite-Q96N96
TrEMBL A0A024RDM6
UniProt Splice Variant
Entrez Gene 221178
UniGene Hs.735225
RefSeq NP_001159743
HUGO HGNC:23222
OMIM 613324
CCDS CCDS53857
HPRD 15427
IMGT
EMBL AK055770 AK074117 AK097217 AK123031 AK160371 AK298717 AK299981 AK301149 AL136963 AL139324 AL359736 AL445985 BC109290 BC109291 BK006072 CH471075
GenPept AAI09291 AAI09292 BAB71009 BAB84943 BAC04977 BAD18714 BAG53856 BAG60873 BAG61802 BAG62740 CAH72289 CAH72290 DAA05848 EAX08331 EAX08332

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca