Version 5.4
Mus musculus Protein: Cep76
Summary
InnateDB Protein IDBP-155793.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep76
Protein Name centrosomal protein 76
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000095149
InnateDB Gene IDBG-155791 (Cep76)
Protein Structure
UniProt Annotation
Function Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Note=Does not localize along the ciliary axoneme. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0046599 regulation of centriole replication
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:1923401
InterPro IPR000008 C2 domain
PFAM PF00168
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0VEJ0
PhosphoSite PhosphoSite-Q0VEJ0
TrEMBL
UniProt Splice Variant
Entrez Gene 225659
UniGene Mm.111928
RefSeq NP_001074542
MGI ID
MGI Symbol Cep76
OMIM
CCDS CCDS37850
HPRD
IMGT
EMBL BC119216 BC119218 CH466528
GenPept AAI19217 AAI19219 EDL09636

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca