Mus musculus Gene: Cep76
Summary
InnateDB Gene IDBG-155791.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep76
Gene Name centrosomal protein 76
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000073542
Encoded Proteins
centrosomal protein 76
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101624:
This gene encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:67617397-67641336
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000097542 ENSMUSP00000095149
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0046599 regulation of centriole replication
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Recruitment of mitotic centrosome proteins and complexes pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Cell Cycle pathway
Mitotic G2-G2/M phases pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Centrosome maturation pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Loss of Nlp from mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q0VEJ0
TrEMBL
UniProt Splice Variant
Entrez Gene 225659
UniGene Mm.111928
RefSeq NM_001081073 XM_006525898 XM_006525899
OMIM
CCDS CCDS37850
HPRD
IMGT
MGI ID MGI:1923401
MGI Symbol Cep76
EMBL BC119216 BC119218 CH466528
GenPept AAI19217 AAI19219 EDL09636
RNA Seq Atlas 225659