Version 5.4
Mus musculus Protein: St3gal5
Summary
InnateDB Protein IDBP-156788.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol St3gal5
Protein Name ST3 beta-galactoside alpha-2,3-sialyltransferase 5
Synonyms [a]2; 3S-T; Siat9;
Species Mus musculus
Ensembl Protein ENSMUSP00000070414
InnateDB Gene IDBG-156786 (St3gal5)
Protein Structure
UniProt Annotation
Function Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide). {ECO:0000269PubMed:12629211}.
Subcellular Localization Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008373 sialyltransferase activity
GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0097503 sialylation
Cellular Component
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID MGI:1339963
InterPro IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
PFAM PF00777
PRINTS
PIRSF PIRSF005557
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88829
PhosphoSite PhosphoSite-O88829
TrEMBL Q91YF4
UniProt Splice Variant
Entrez Gene 20454
UniGene Mm.38248
RefSeq NP_001030305
MGI ID
MGI Symbol St3gal5
OMIM
CCDS CCDS20237
HPRD
IMGT
EMBL AB013302 AB018048 AF119416 AK012961 AK159000 AK165726 BC138557 BC138559 Y15003 Y18021 Y18022 Y18023
GenPept AAF66147 AAI38558 AAI38560 BAA33491 BAA76467 BAB28571 BAE34763 BAE38355 CAA75235 CAA75236 CAC79653 CAC79654 CAC79655

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca