Version 5.4
| Mus musculus Gene: St3gal5 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-156786.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | St3gal5 | ||||||||
| Gene Name | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | ||||||||
| Synonyms | [a]2; 3S-T; Siat9 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000056091 | ||||||||
| Encoded Proteins |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115525:
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 6:72097592-72154571 | ||||||||
| Strand | Forward strand | ||||||||
| Band | C1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of substrates in N-glycan biosythesis pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
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| KEGG |
Glycosphingolipid biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
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| KEGG |
Glycosphingolipid biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | O88829 | ||||||||
| TrEMBL | Q91YF4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 20454 | ||||||||
| UniGene | Mm.38248 | ||||||||
| RefSeq | NM_001035228 NM_011375 XM_006505816 XM_006505817 XM_006505818 XM_006505821 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS20237 CCDS39510 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1339963 | ||||||||
| MGI Symbol | St3gal5 | ||||||||
| EMBL | AB013302 AB018048 AF119416 AK012961 AK159000 AK165726 BC138557 BC138559 Y15003 Y18021 Y18022 Y18023 | ||||||||
| GenPept | AAF66147 AAI38558 AAI38560 BAA33491 BAA76467 BAB28571 BAE34763 BAE38355 CAA75235 CAA75236 CAC79653 CAC79654 CAC79655 | ||||||||
| RNA Seq Atlas | 20454 | ||||||||